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One study showed that topical treatment twice a day for 3 months with 5% glycolic acid at pH 2.8 affected surface and epidermal changes, while the same treatment, but with a 12% reached deeper and influenced both the epidermis and the deeper dermis layer, and resulted in increased epidermal and dermal firmness and thickness

& Frey, S

Defects in the OCTN2 gene cause primary carnitine deficiency, further emphasizing the strategic position of OCTN2 in maintaining carnitine homeostasis [165]